Our Publications

Wilson EN, Wang C, Swarovski MS, Zera KA, Ennerfelt HE, Wang Q, Chaney A, Gauba E, Ramos Benitez JA, Le Guen Y, Minhas PS, Panchal M, Tan YJ, Blacher E, A Iweka C, Cropper H, Jain P, Liu Q, Mehta SS, Zuckerman AJ, Xin M, Umans J, Huang J, Durairaj AS, Serrano GE, Beach TG, Greicius MD, James ML, Buckwalter MS, McReynolds MR, Rabinowitz JD, Andreasson KI. TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models. Nat Neurosci. 2024 May;27(5):873-885. doi: 10.1038/s41593-024-01610-w. Epub 2024 Mar 27. PubMed PMID: 38539014; PubMed Central PMCID: PMC11102654.

Kara N, Iweka CA, Blacher E. Chrono-Gerontology: Integrating Circadian Rhythms and Aging in Stroke Research. Adv Biol (Weinh). 2023 Jul 6:e2300048. doi: 10.1002/adbi.202300048. Epub ahead of print. PMID: 37409422.

Iweka CA, Seigneur E, Hernandez AL, Paredes SH, Cabrera M, Blacher E, Pasternak CT, Longo FM, De Lecea L, and Andreasson KI. Myeloid deficiency of the intrinsic clock protein BMAL1 accelerates cognitive aging by disrupting microglial synaptic pruning. J Neuroinflammation. 2023 Feb 24;20(1):48. doi: 10.1186/s12974-023-02727-8. PMID: 36829230; PMCID: PMC9951430.

Blacher E, Tsai C, Litichevskiy L, Shipony Z, Iweka CA, Schneider KM, Chuluun B, Heller HC, Menon V, Thaiss CA, Andreasson KI. Aging disrupts circadian gene regulation and function in macrophages. Nat Immunol. 2021 Dec 23. doi: 10.1038/s41590-021-01083-0. Epub ahead of print. PMID: 34949832.

Iweka CA, Hussein RK, Yu P, Katagiri Y, Geller HM. The lipid phosphatase-like protein PLPPR1 associates with RhoGDI1 to modulate RhoA activation in response to axon growth inhibitory molecules. J Neurochem. 2021 Dec 15. doi: 10.1111/jnc.15271. Epub ahead of print. PMID: 33320336.

Tilve S, Iweka CA, Bao J, Hawken N, Mencio CP, Geller HM. Phospholipid phosphatase related 1 (PLPPR1) increases cell adhesion through modulation of Rac1 activity. Exp Cell Res. 2020 Apr 15;389(2):111911. doi: 10.1016/j.yexcr.2020.111911. Epub 2020 Feb 14. PMID: 32061832; PMCID: PMC7132996. 

Nagase H, Higashi SL, Iweka CA, Pearson CS, Hirata Y, Geller HM, Katagiri Y. Reliable and sensitive detection of glycosaminoglycan chains with immunoblots. Glycobiology. 2020 Jul 02; 31(2):116–125PMID: 32614944. doi: 10.1093/glycob/cwaa060.

Main BS, Villapol S, Sloley SS, Barton DJ, Parsadanian M, Agbaegbu C, Stefos K, McCann MS, Washington PM, Rodriguez OC, Burns MP. Apolipoprotein E4 impairs spontaneous blood brain barrier repair following traumatic brain injury. Mol Neurodegener. 2018 Apr 4;13(1):17. doi: 10.1186/s13024-018-0249-5. PMID: 29618365; PMCID: PMC5885297.

Yu P, Agbaegbu C, Malide DA, Wu X, Katagiri Y, Hammer JA, Geller HM. Cooperative interactions of LPPR family members in membrane localization and alteration of cellular morphology. J Cell Sci. 2015 Sep 1;128(17):3210-22. doi: 10.1242/jcs.169789. Epub 2015 Jul 16. PMID: 26183180; PMCID: PMC4582190.