Synchronizing Life's Rhythms

Unveiling the Power of the Circadian Clock in Aging and Disease

What We Do

Our research focuses on understanding the mechanisms regulated by the circadian clock that become impaired as we age, and leveraging our knowledge to better understand healthy aging as well as the pathophysiology of diseases such as age-related immune dysfunction, metabolic and sleep disorders, stroke and vascular dementia.

Why We do it

The circadian clock is a critical aspect of every living organism, from bacteria to humans, synchronizing all physiological mechanisms within an organism with the external environment to maintain homeostasis. This process allows every cell/tissue/organ to anticipate changes in its immediate environment to facilitate an appropriate response. Unfortunately, as we age, our circadian clock function declines, increasing our risk for disease.

Our research goal is to identify the specific mechanisms under circadian clock control that influence the aging and age-related disease processes, specifically in the immune and nervous systems, and to use this knowledge to develop therapeutic strategies to promote healthy aging and address age-related pathologies.